Answer the following questions:
What systems are affected by stress?
Describe the General Adaptation Syndrome.
Why does stress dismantle the immune system?
What is a glucocorticoid? What are the triggers for glucocorticoid release?
Describe the classical glucocorticoid cascade hypothesis for brain damage (aging). What data supports this hypothesis? What data is inconsistent with this hypothesis?
Describe at least two pathways for negative-feedback regulation of the HPA axis.
What are the functions of the Glucocorticoid and Mineralocorticoid receptors (GR and MR)?
Define the HPA axis.
What effect does adrenalectomy have on glucocorticoid levels?
Why might neuronal atrophy be viewed as neuroprotective?
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